The heparin binding PECAM-1 adhesion molecule is expressed by CD34+ hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes.

@article{Watt1993TheHB,
  title={The heparin binding PECAM-1 adhesion molecule is expressed by CD34+ hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes.},
  author={Suzanne M. Watt and J. E. Williamson and Helen Genevier and James Fawcett and David Ll. Simmons and Antoinette Hatzfeld and Stephen A. Nesbitt and Deirdre R. Coombe},
  journal={Blood},
  year={1993},
  volume={82 9},
  pages={2649-63}
}
The platelet-endothelial cell adhesion molecule-1 (PE-CAM-1), defined by the CD31 monoclonal antibody (MoAb), was initially described as a cell-cell adhesion molecule mediating both homotypic and heterotypic adhesion. In this report, we show that enriched CD34+ human hematopoietic progenitor cell populations, containing early myeloid, erythroid, and multipotential progenitor cells, are CD31+. Analyses of CD34+ cell lines representing early myeloid, multipotential, and pre-pre-B-lymphoid… CONTINUE READING
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