The hemolymph coagulation system in invertebrate animals

@article{Iwanaga1986TheHC,
  title={The hemolymph coagulation system in invertebrate animals},
  author={S. Iwanaga and T. Morita and T. Miyata and Takanori Nakamura and J. Aketagawa},
  journal={Journal of Protein Chemistry},
  year={1986},
  volume={5},
  pages={255-268}
}
A hemocyte lysate from horseshoe crab produced a gel, when exposed to Gram-negative bacterial endotoxins. This gelation reaction of the lysate, so-called Limulus test, has been widely employed as a simple and very sensitive assay method for endotoxins. Recent biochemical studies on the principle of Limulus test indicate that the hemocytes contain several serine protease zymogens, which constitute a coagulation cascade triggered by endotoxins, and that there is a (1 → 3)-β-d-glucan-mediated… Expand
Molecular mechanism of hemolymph clotting system in Limulus.
Limulus proclotting enzyme.
Limulus clotting factor B.
Horseshoe crab transglutaminase.
The limulus clotting reaction.
  • S. Iwanaga
  • Biology, Medicine
  • Current opinion in immunology
  • 1993
Role of Hemocyte‐Derived Granular Components in Invertebrate Defense a
Biological activities of anti-LPS factor and LPS binding peptide from horseshoe crab amoebocytes.
Characterization of a clotting protein, isolated from plasma of the freshwater crayfish Pacifastacus leniusculus.
Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
...
1
2
3
...

References

SHOWING 1-10 OF 25 REFERENCES
Primary structure of limulus anticoagulant anti-lipopolysaccharide factor.
...
1
2
3
...