The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the RsaI polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro.

@article{Hamada1995TheHR,
  title={The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the RsaI polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro.},
  author={Gerson Shigeaki Hamada and Haruhiko Sugimura and Isamu Suzuki and Kazuo Nagura and Etsuko Kiyokawa and Tsuyoshi Iwase and Masao Tanaka and Takehiro Takahashi and Shinji Watanabe and Isamu Kino},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={1995},
  volume={4 1},
  pages={63-7}
}
Ile-Val polymorphism in exon 7 of cytochrome P450IA1 (CypIA1) and RsaI polymorphism of cytochrome P450IIE1 (CypIIE1) were examined in a case-control study of lung cancer in Rio de Janeiro, Brazil. The Val-containing genotype in exon 7 of CypIA1 was found to be associated with lung cancer in this population (odds ratio, 2.26; 95% confidence interval, 1.14-4… CONTINUE READING