The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.

@article{Gonzalez2009TheHS,
  title={The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.},
  author={Oscar J. Avella Gonzalez and Vanessa Fontanes and Santanu Raychaudhuri and Rachel R Ogorzalek Loo and Joseph R Loo and Vaithilingaraja Arumugaswami and Ren Sun and Asim K. Dasgupta and Samuel French},
  journal={Hepatology},
  year={2009},
  volume={50 6},
  pages={1756-64}
}
UNLABELLED The hepatitis C viral (HCV) genome is translated through an internal ribosome entry site (IRES) as a single polyprotein precursor that is subsequently cleaved into individual mature viral proteins. Nonstructural protein 5A (NS5A) is one of these proteins that has been implicated in regulation of viral genome replication, translation from the viral IRES and viral packaging. We sought to identify cellular proteins that interact with NS5A and determine whether these interactions may… CONTINUE READING
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