The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol.

@article{Mautner1992TheHI,
  title={The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol.},
  author={Sven Mautner and Jos{\'e} Antonio Serrano S{\'a}nchez and Daniel J. Rader and Gerlinde Mautner and V{\'i}ctor J. Ferrans and Donald S. Fredrickson and Hollis Brian Brewer and William Clifford Roberts},
  journal={American journal of clinical pathology},
  year={1992},
  volume={98 2},
  pages={
          191-8
        }
}
Cardiac necropsy findings are described in a 72-year-old man with Tangier disease whose plasma total cholesterol levels averaged 70 mg/dL, low-density lipoprotein cholesterol level was 45 mg/dL, and high-density lipoprotein cholesterol level was 1.4 mg/dL, and who had coronary artery bypass grafting for severe atherosclerotic coronary artery disease. At necropsy, 24 of the 72 (33%) 5-mm segments of the 4 major (right, left main, left anterior descending, and left circumflex) native coronary… CONTINUE READING
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