The heads of the measles virus attachment protein move to transmit the fusion-triggering signal

@inproceedings{Navaratnarajah2011TheHO,
  title={The heads of the measles virus attachment protein move to transmit the fusion-triggering signal},
  author={Chanakha K. Navaratnarajah and Numan Oezguen and Levi J. Rupp and L. A. Kay and Vincent H J Leonard and Werner A Braun and Roberto Cattaneo},
  booktitle={Nature Structural &Molecular Biology},
  year={2011}
}
The measles virus entry system, consisting of attachment (hemagglutinin, H) and fusion proteins, operates by means of a variety of natural and targeted receptors; however, the mechanism that triggers fusion of the viral envelope with the plasma membrane is not understood. Here, we tested a model proposing that the two heads of an H dimer, which are covalently linked at their base, after binding two receptor molecules, move relative to each other to transmit the fusion-triggering signal. Indeed… CONTINUE READING

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