The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line

@article{Adey2013TheHG,
  title={The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line},
  author={Andrew C. Adey and Joshua N. Burton and Jacob O. Kitzman and Joseph B. Hiatt and Alexandra P. Lewis and Beth K. Martin and Ruolan Qiu and Choli Lee and Jay A. Shendure},
  journal={Nature},
  year={2013},
  volume={500},
  pages={207 - 211}
}
The HeLa cell line was established in 1951 from cervical cancer cells taken from a patient, Henrietta Lacks. This was the first successful attempt to immortalize human-derived cells in vitro. The robust growth and unrestricted distribution of HeLa cells resulted in its broad adoption—both intentionally and through widespread cross-contamination—and for the past 60 years it has served a role analogous to that of a model organism. The cumulative impact of the HeLa cell line on research is… 
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Haplotype resolution at the single-cell level
  • Andrew C. Adey
  • Biology, Medicine
    Proceedings of the National Academy of Sciences
  • 2017
One of the most rapidly advancing areas in genomics in recent years has been the explosion of platforms to assess properties at the single-cell level. The driving force behind these advancements has
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