The hamster (Mesocricetus auratus) as experimental model in Chagas' disease: parasitological and histopathological studies in acute and chronic phases of Trypanosoma cruzi infection.

@article{Ramrez1994TheH,
  title={The hamster (Mesocricetus auratus) as experimental model in Chagas' disease: parasitological and histopathological studies in acute and chronic phases of Trypanosoma cruzi infection.},
  author={Lu{\'i}s Eduardo Ram{\'i}rez and Eliane Lages-Silva and Jos{\'e} Maria Soares J{\'u}nior and Edmundo Chapadeiro},
  journal={Revista da Sociedade Brasileira de Medicina Tropical},
  year={1994},
  volume={27 3},
  pages={163-9}
}
This research characterizes the acute and chronic phases of Chagas' disease in hamster through parasitological and histopathological studies. The acute phase was achieved with 44 young hamsters injected intraperitoneally with 100,000 blood trypomastigotes of Benedito and Y strains of T. cruzi. The chronic phase was induced in 46 hamsters injected intraperitoneally with 35,000 trypomastigotes of Vicentia, Benedito and Y strains. Animals were sacrificed at regular intervals of 24 hours of acute… CONTINUE READING

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