The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea‐pig ileum

@article{Capasso2006TheHH,
  title={The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea‐pig ileum},
  author={R. Capasso and F. Borrelli and F. Capasso and D. Siebert and D. Stewart and J. Zjawiony and A. Izzo},
  journal={Neurogastroenterology & Motility},
  year={2006},
  volume={18}
}
Abstract  Salvia divinorum is a widespread hallucinogenic herb traditionally employed for divination, as well as a medicament for several disorders including disturbances of gastrointestinal motility. In the present study we evaluated the effect of a standardized extract from the leaves of S. divinorum (SDE) on enteric cholinergic transmission in the guinea‐pig ileum. SDE reduced electrically evoked contractions without modifying the contractions elicited by exogenous acetylcholine, thus… Expand
61 Citations
The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A reduce inflammation‐induced hypermotility in mice
  • R. Capasso, F. Borrelli, +5 authors A. Izzo
  • Chemistry, Medicine
  • Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2008
Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo
The antinociceptive effect of salvinorin A in mice.
Neuropharmacology of the Naturally Occurring κ-Opioid Hallucinogen Salvinorin A
Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis‐induced hypermotility: cross‐talk between κ‐opioid and cannabinoid CB1 receptors
Inhibitory effect of the herbal antidepressant St. John’s wort (Hypericum perforatum) on rat gastric motility
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 30 REFERENCES
Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist
  • B. Roth, K. Baner, +5 authors R. Rothman
  • Chemistry
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2002
Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.
  • B. Roth, K. Baner, +5 authors R. Rothman
  • Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2002
Hallucinogens and dissociative agents naturally growing in the United States.
  • J. Halpern
  • Medicine, Chemistry
  • Pharmacology & therapeutics
  • 2004
...
1
2
3
...