• DOI:10.1111/j.1365-2982.2007.00994.x
Corpus ID: 25081755

The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A reduce inflammation‐induced hypermotility in mice

@article{Capasso2008TheHH,
  title={The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A reduce inflammation‐induced hypermotility in mice},
  author={R. Capasso and F. Borrelli and J. Zjawiony and L. Kutrzeba and G. Aviello and G. Sarnelli and F. Capasso and A. Izzo},
  journal={Neurogastroenterology & Motility},
  year={2008},
  volume={20}
}

• R. Capasso, F. Borrelli, +5 authors A. Izzo
• Published 2008
• Chemistry, Medicine
• Neurogastroenterology & Motility

Abstract  The hallucinogenic plant Salvia divinorum has been used for medical treatments of gastrointestinal disorders. Here, we evaluated the effect of a standardized extract from the leaves of Salvia divinorum (SDE) and of its active ingredient salvinorin A on motility in vivo, both in physiological states and during croton oil‐induced intestinal inflammation. SDE (1–100 mg kg−1) significantly inhibited motility only in inflamed, but not in control, mice. In control mice, salvinorin A (0.01… Expand

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