The haemodynamic and metabolic effects of epinephrine in experimental hyperdynamic septic shock

@article{Giantomasso2005TheHA,
  title={The haemodynamic and metabolic effects of epinephrine in experimental hyperdynamic septic shock},
  author={David Di Giantomasso and Rinaldo Bellomo and Clive N. May},
  journal={Intensive Care Medicine},
  year={2005},
  volume={31},
  pages={454-462}
}
To study the effect of epinephrine (EPI) infusion on vital organ blood flow and metabolic variables during sepsis. Randomised placebo-controlled animal trial in an animal laboratory. Seven merino cross-ewes. Chronic implantation of flow probes (aorta, renal, mesenteric and coronary artery and sagittal sinus). Induction of sepsis by intravenous injection of E. coli. Random allocation of sheep to EPI (0.4 µg kg−1 min−1) or vehicle for 6 h. E. coli induced hypotension and hyperlactataemia and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

The use of vasopressors and inotropes in the emergency medical treatment of shock.

Emergency medicine clinics of North America • 2008
View 5 Excerpts
Highly Influenced

Hyperlactatemia and Cardiac Surgery.

The journal of extra-corporeal technology • 2017

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Similar Papers

Loading similar papers…