The gut microbiota as an environmental factor that regulates fat storage.

  title={The gut microbiota as an environmental factor that regulates fat storage.},
  author={Fredrik B{\"a}ckhed and Hao Ding and Ting Wang and Lora V. Hooper and Gou Young Koh and Andr{\'a}s D Nagy and Clay F. Semenkovich and Jeffrey I. Gordon},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={101 44},
  • F. BäckhedHao Ding J. Gordon
  • Published 2 November 2004
  • Biology
  • Proceedings of the National Academy of Sciences of the United States of America
New therapeutic targets for noncognitive reductions in energy intake, absorption, or storage are crucial given the worldwide epidemic of obesity. [] Key Result Studies of GF and conventionalized mice revealed that the microbiota promotes absorption of monosaccharides from the gut lumen, with resulting induction of de novo hepatic lipogenesis.

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