The gut microbiota — masters of host development and physiology

@article{Sommer2013TheGM,
  title={The gut microbiota — masters of host development and physiology},
  author={Felix Sommer and Fredrik B{\"a}ckhed},
  journal={Nature Reviews Microbiology},
  year={2013},
  volume={11},
  pages={227-238}
}
Establishing and maintaining beneficial interactions between the host and its associated microbiota are key requirements for host health. Although the gut microbiota has previously been studied in the context of inflammatory diseases, it has recently become clear that this microbial community has a beneficial role during normal homeostasis, modulating the host's immune system as well as influencing host development and physiology, including organ development and morphogenesis, and host… 
Microbial Activities and Intestinal Homeostasis: A Delicate Balance Between Health and Disease
  • C. Ohland, C. Jobin
  • Biology, Medicine
    Cellular and molecular gastroenterology and hepatology
  • 2015
The role of the gut microbiome during host ageing
TLDR
It is revealed for the first time that gut microbes can modulate ageing, opening new questions and opportunities to uncover novel ageing-modulating mechanisms and to design anti-ageing interventions by targeting the gut microbiota.
Gut Microbiota Dysbiosis and COVID-19: Possible Links
  • B. Aktas
  • Medicine, Biology
    Reference Module in Food Science
  • 2021
Effects of the modulation of microbiota on the gastrointestinal immune system and bowel function.
The gastrointestinal tract harbors a tremendous number and variety of commensal microbiota. The intestinal mucosa simultaneously absorbs essential nutrients and protects against detrimental antigens
Gut Microbiotas and Host Evolution: Scaling Up Symbiosis.
  • M. Shapira
  • Biology, Environmental Science
    Trends in ecology & evolution
  • 2016
Linking Microbiota to Human Diseases: A Systems Biology Perspective
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 145 REFERENCES
Functional interactions between the gut microbiota and host metabolism
TLDR
Through increased knowledge of the mechanisms involved in the interactions between the microbiota and its host, the world will be in a better position to develop treatments for metabolic disease.
The gut microbiota shapes intestinal immune responses during health and disease
TLDR
Findings indicating that developmental aspects of the adaptive immune system are influenced by bacterial colonization of the gut are discussed, and the possibility that the mammalian immune system, which seems to be designed to control microorganisms, is in fact controlled by microorganisms is raised.
Immune adaptations that maintain homeostasis with the intestinal microbiota
TLDR
The unique adaptations of the intestinal immune system that maintain homeostatic interactions with a diverse resident microbiota are discussed.
Microbiota, Disease, and Back to Health: A Metastable Journey
TLDR
The gut microbiota affects many immune-related diseases; the next step is to harness this knowledge for therapeutics and understand the basis for changes, how they relate to disease risk or activity, and the mechanisms by which the symbiotic state of colonization resistance and host homeostasis is restored.
Interactions Between the Microbiota and the Immune System
TLDR
Advances in understanding of the interactions between resident microbes and the immune system are reviewed and the implications for human health are reviewed.
The Commensal Microbiota Drives Immune Homeostasis
TLDR
Focusing on the strategies that microbes use to keep the authors' immune system healthy, as opposed to trying to correct the immune imbalances caused by dysbiosis, may prove to be a more astute and efficient way of treating immune-mediated disease.
Voices from within: gut microbes and the CNS
TLDR
Understanding of the mechanisms underlying microbiome–gut–brain communication will provide new insight into the symbiotic relationship between gut microbiota and their mammalian hosts and help to identify the potential for microbial-based therapeutic strategies to aid in the treatment of mood disorders.
The Gut Microbiota and Mucosal T Cells
TLDR
This review focuses on the gut microbiota's influence on the development and function of mucosal T cells subsets, specifically intraepithelial lymphocytes and lamina propria CD4 T cells.
[Gut microbiota in health and disease].
...
1
2
3
4
5
...