The gut microbiome in human neurological disease: A review

@article{Tremlett2017TheGM,
  title={The gut microbiome in human neurological disease: A review},
  author={H. Tremlett and K. C. Bauer and Silke Appel-Cresswell and B. Finlay and E. Waubant},
  journal={Annals of Neurology},
  year={2017},
  volume={81}
}
  • H. Tremlett, K. C. Bauer, +2 authors E. Waubant
  • Published 2017
  • Biology, Medicine
  • Annals of Neurology
  • Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and viruses. These microorganisms collectively form the human microbiota, with most colonizing the gut. Recent technological advances, open access data libraries, and application of high‐throughput sequencing have allowed these microbes to be identified and their contribution to neurological health to be examined. Emerging evidence links… CONTINUE READING
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    References

    SHOWING 1-10 OF 147 REFERENCES
    The role of microbiome in central nervous system disorders
    • 396
    • PDF
    The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease.
    • 112
    • PDF
    Gut microbiota are related to Parkinson's disease and clinical phenotype
    • 714
    • Highly Influential
    • PDF
    Alterations of the human gut microbiome in multiple sclerosis
    • 449
    • PDF
    Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota (S37.005)
    • 1
    Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model
    • 98
    • Highly Influential
    • PDF
    Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
    • 1,026
    • PDF
    Control of brain development, function, and behavior by the microbiome.
    • 424
    • PDF