The gut microbiome in autoimmunity: Sex matters.

  title={The gut microbiome in autoimmunity: Sex matters.},
  author={Andr{\'e}s Felipe G{\'o}mez and David H. Luckey and Veena Taneja},
  journal={Clinical immunology},
  volume={159 2},
Autoimmune diseases like rheumatoid arthritis are multifactorial in nature, requiring both genetic and environmental factors for onset. Increased predisposition of females to a wide range of autoimmune diseases points to a gender bias in the multifactorial etiology of these disorders. However, the existing evidence to date has not provided any conclusive mechanism of gender-bias beyond the role of hormones and sex chromosomes. The gut microbiome, which impacts the innate and adaptive branches… CONTINUE READING
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