The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?

@inproceedings{Houser2016TheGA,
  title={The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?},
  author={Madelyn C. Houser and Mal{\'u} G. Tansey},
  booktitle={npj Parkinson's Disease},
  year={2016}
}
The state of the intestinal environment can have profound effects on the activity of the central nervous system through the physiological contributions of the microbiota, regulation of intestinal barrier function, and altered activity of peripheral neurons. The common language employed for much of the gut-brain communication is the modulation of immune activity. Chronic proinflammatory immune activity is increasingly being recognized as a fundamental element of neurodegenerative disorders, and… CONTINUE READING