The guanine and cytosine content of genomic DNA and bacterial evolution.

  title={The guanine and cytosine content of genomic DNA and bacterial evolution.},
  author={Akira Muto and S. Osawa},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={84 1},
The genomic guanine and cytosine (G + C) content of eubacteria is related to their phylogeny. The G + C content of various parts of the genome (protein genes, stable RNA genes, and spacers) reveals a positive linear correlation with the G + C content of their genomic DNA. However, the plotted correlation slopes differ among various parts of the genome or among the first, second, and third positions of the codons depending on their functional importance. Facts suggest that biased mutation… CONTINUE READING
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