The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells.

@article{Berger2002TheGO,
  title={The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells.},
  author={C. Berger and D. Hanlon and D. Kanada and M. Dhodapkar and Vivian A Lombillo and Nianci Wang and I. Christensen and G. Howe and J. Crouch and Paul El-Fishawy and R. Edelson},
  journal={Blood},
  year={2002},
  volume={99 8},
  pages={
          2929-39
        }
}
  • C. Berger, D. Hanlon, +8 authors R. Edelson
  • Published 2002
  • Medicine, Biology
  • Blood
  • In the initial stage of cutaneous T-cell lymphoma (CTCL), proliferating CTCL cells are concentrated in the epidermis in close association with an immature dendritic cell (DC), the Langerhans cell. Because long-term in vitro culture of CTCL cells has proven difficult, the in vivo association with the major antigen-presenting cell (APC) of the epidermis has been postulated to play a role in directly stimulating the clonal T-cell proliferation. We report that CTCL cells can be reproducibly grown… CONTINUE READING

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