The growth hormone secretagogue hexarelin improves cardiac function in rats after experimental myocardial infarction.

@article{Tivesten1998TheGH,
  title={The growth hormone secretagogue hexarelin improves cardiac function in rats after experimental myocardial infarction.},
  author={{\AA}sa Tivesten and Entela Bollano and Kenneth Caidahl and Vuk G. Kujacic and Xiang Ying Sun and Thomas Hedner and {\AA}ke Hjalmarson and Bertil Bengtsson and Jorgen Isgaard},
  journal={Endocrinology},
  year={1998},
  volume={141 1},
  pages={
          60-6
        }
}
Several studies have shown that GH can enhance cardiac performance in rats after experimental myocardial infarction and in humans with congestive heart failure. In the present study, the hemodynamic effects of hexarelin (Hex), an analog of GH-releasing peptide-6 and a potent GH secretagogue, were compared with the effects of GH. Four weeks after ligation of the left coronary artery male rats were treated sc twice daily with hexarelin [10 microg/kg x day (Hex10) or 100 microg/kg x day (Hex100… CONTINUE READING
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