The growth-hormone-releasing hormone receptor: signal transduction, gene expression, and physiological function in growth regulation.

@article{Mayo1996TheGH,
  title={The growth-hormone-releasing hormone receptor: signal transduction, gene expression, and physiological function in growth regulation.},
  author={Kelly E. Mayo and Tricia L Miller and V I Dealmeida and Jingfang Zheng and Paul A Godfrey},
  journal={Annals of the New York Academy of Sciences},
  year={1996},
  volume={805},
  pages={184-203}
}
We now summarize key issues that we have investigated and highlight additional areas that need to be addressed. We are interested in two basic aspects of the GHRH pathway, those occurring in the brain, involving the synthesis of GHRH, and those occurring in the pituitary, involving signaling by GHRH. We have a long-term interest in the activity and regulation of the hypothalamic neurosecretory cells that synthesize GHRH. With respect to human disease, it is interesting that, despite the primal… CONTINUE READING

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