The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism.

@article{Cohen2007TheGB,
  title={The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism.},
  author={Sigal Ben-Zaken Cohen and Peter D. Par{\'e} and Shu Fan Paul Man and Don D. Sin},
  journal={American journal of respiratory and critical care medicine},
  year={2007},
  volume={176 2},
  pages={113-20}
}
Smoking-related lung diseases such as chronic obstructive pulmonary disease (COPD) and lung cancer are growing epidemics in women in the United States and elsewhere. Although some of this disturbing trend in women can be attributed to changing smoking habits, there is emerging evidence that women may be biologically more susceptible to the harmful effects of cigarette smoke than are men. Estrogen and related compounds may up-regulate the expression of cytochrome P450 (CYP) enzymes in lungs and… CONTINUE READING

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