The granulocyte colony-stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 but not flt-3 ligand.

@article{Liu1997TheGC,
  title={The granulocyte colony-stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 but not flt-3 ligand.},
  author={Fulu Liu and Jennifer Poursine-Laurent and Daniel C. Link},
  journal={Blood},
  year={1997},
  volume={90 7},
  pages={
          2522-8
        }
}
Hematopoietic progenitor cells (HPC) can be mobilized from the bone marrow into the peripheral circulation in response to a number of stimuli including hematopoietic growth factors, cytotoxic agents, and certain chemokines. Despite significant differences in their biological activities, these stimuli result in the mobilization of HPC with a similar phenotype, suggesting that a common mechanism for mobilization may exist. In this study, the role of granulocyte colony-stimulating factor (G-CSF… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 32 REFERENCES

Ashman ing factor-induced mobilization of hematopoietic stem cells and progenitor cells into blood in mice

L To, D Haylock, T Dowse, P Simmons, S Trimboli
  • Blood 89:3186,
  • 1997

in mice

C Juttner, F Liu, +3 authors DC Link
  • 1997

of endogenous cytokine concentrations after high - dose chemotherapy with autologous bone marrow support

S Neben, K Marcus, +5 authors W Hunstein
  • blood
  • 1997

tor and chemoattractant for neutrophils.37

L To, D Haylock, P Simmons, C Juttner
  • Blood 89:2233,
  • 1997

CharacterizationTsukamoto A : The unexpected G 0 / G 1 cell cycle status of mobilized hematopoietic stem cells from peripheral

J Rabinowitz, W Petros, A Stuart, W Peters
  • Blood
  • 1996

Flt - tor and its receptor

G Molineux, C McCrea, X Yan, P Kerzic, I McNiece
  • Blood
  • 1996