The good initial response to therapy with a combination of traditional disease-modifying antirheumatic drugs is sustained over time: the eleven-year results of the Finnish rheumatoid arthritis combination therapy trial.

@article{Rantalaiho2009TheGI,
  title={The good initial response to therapy with a combination of traditional disease-modifying antirheumatic drugs is sustained over time: the eleven-year results of the Finnish rheumatoid arthritis combination therapy trial.},
  author={Vappu Marianna Rantalaiho and M. Korpela and Pekka J Hannonen and Hannu Kautiainen and Salme K J{\"a}rvenp{\"a}{\"a} and Marjatta Leirisalo-Repo and Markku Hakala and Kari T Puolakka and Heikki A Julkunen and Riitta Luosuj{\"a}rvi and Timo M{\"o}tt{\"o}nen},
  journal={Arthritis and rheumatism},
  year={2009},
  volume={60 5},
  pages={1222-31}
}
OBJECTIVE To evaluate the evolution of functional and clinical outcomes over 11 years in patients with early rheumatoid arthritis (RA) initially treated with a combination of 3 disease-modifying antirheumatic drugs (DMARDs) or with a single DMARD. METHODS A cohort of 199 patients with early active RA were initially randomized to receive treatment with a combination of methotrexate, sulfasalazine, and hydroxychloroquine with prednisolone or treatment with a single DMARD (initially… CONTINUE READING