The gonadotropin-releasing hormone antagonist (Nal-Glu) acutely blocks the luteinizing hormone surge but allows for resumption of folliculogenesis in normal women.

@article{Ditkoff1991TheGH,
  title={The gonadotropin-releasing hormone antagonist (Nal-Glu) acutely blocks the luteinizing hormone surge but allows for resumption of folliculogenesis in normal women.},
  author={Edward C. Ditkoff and D L Cassidenti and Richard J. Paulson and Mark V. Sauer and W. L. Paul and Jean Rivier and Samuel Yen and Rog{\'e}rio Souza Lobo},
  journal={American journal of obstetrics and gynecology},
  year={1991},
  volume={165 6 Pt 1},
  pages={1811-7}
}
The gonadotropin-releasing hormone antagonist offers several advantages over the use of the agonist and allows several physiologic questions to be addressed. In this study, we evaluated the ability of Nal-Glu to acutely inhibit the luteinizing hormone surge and prevent ovulation. We also assessed whether recovery of the follicle would be possible after several days of gonadotropin deprivation and estradiol decrement. Eight normal ovulatory women were randomized to control or Nal-Glu-treated… CONTINUE READING

From This Paper

Topics from this paper.
14 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…