The glyoxylate cycle is required for fungal virulence

@article{Lorenz2001TheGC,
  title={The glyoxylate cycle is required for fungal virulence},
  author={Michael C. Lorenz and Gerald R. Fink},
  journal={Nature},
  year={2001},
  volume={412},
  pages={83-86}
}
Candida albicans, a normal component of the mammalian gastrointestinal flora, is responsible for most fungal infections in immunosuppressed patients. Candida is normally phagocytosed by macrophages and neutrophils, which secrete cytokines and induce hyphal development in this fungus. Neutropenic patients, deficient in these immune cells, are particularly susceptible to systemic candidiasis. Here we use genome-wide expression profiles of the related yeast Saccharomyces cerevisiae to obtain a… 
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