The glycosylation profile of interleukin-2 activated human lymphocytes correlates to their anti-tumor activity.

@article{Voshol1996TheGP,
  title={The glycosylation profile of interleukin-2 activated human lymphocytes correlates to their anti-tumor activity.},
  author={H Voshol and Hub F. J. Dullens and Willem den Otter and Johannes F. G. Vliegenthart},
  journal={Anticancer research},
  year={1996},
  volume={16 1},
  pages={155-9}
}
BACKGROUND Natural killer cells display spontaneous, non-MHC-restricted cytotoxicity against tumour cells, which is strongly enhanced after incubation with IL-2. The molecular background of the increased anti-tumour activity of these lymphokine-activated killer cells is still only partly understood. MATERIALS AND METHODS In this paper, investigation has been made of the correlation between cell surface glycosylation and anti-tumour activity of LAK cells by stimulating peripheral blood… CONTINUE READING

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