The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain.

@article{McKenna2007TheGC,
  title={The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain.},
  author={Mary C McKenna},
  journal={Journal of neuroscience research},
  year={2007},
  volume={85 15},
  pages={3347-58}
}
Although glutamate is usually thought of as the major excitatory neurotransmitter in brain, it is important to note that glutamate has many other fates in brain, including oxidation for energy, incorporation into proteins, and formation of glutamine, gamma-aminobutyric acid (GABA), and glutathione. The compartmentation of glutamate in brain cells is complex and modulated by the presence and concentration of glutamate per se as well as by other metabolites. Both astrocytes and neurons… CONTINUE READING
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