The glucose-galactose paradox in neonatal murine hepatic glycogen synthesis.

@article{Kunst1989TheGP,
  title={The glucose-galactose paradox in neonatal murine hepatic glycogen synthesis.},
  author={C Kunst and Robert Kliegman and Cleide Enoir Petean Trindade},
  journal={The American journal of physiology},
  year={1989},
  volume={257 5 Pt 1},
  pages={E697-703}
}
In adults glucose incorporation to glycogen is indirect after recycling from lactate. In neonates galactose entry to glycogen exceeds that for glucose, but the pathway is unknown. The pathway of hexose incorporation to glycogen was studied in 5-7-day-old rats and 6-h-old rats injected intraperitoneally (IP) with either double-labeled [6-3H]glucose (nonrecycling), [U-14C]glucose (recycling), or [6-3H]glucose and [U-14C]galactose in saline. In another group of pups, 1 g/kg of glucose or galactose… CONTINUE READING