The glucose-6-phosphatase system.

  title={The glucose-6-phosphatase system.},
  author={Emile van Schaftingen and Isabelle Gerin},
  journal={The Biochemical journal},
  volume={362 Pt 3},
Glucose-6-phosphatase (G6Pase), an enzyme found mainly in the liver and the kidneys, plays the important role of providing glucose during starvation. Unlike most phosphatases acting on water-soluble compounds, it is a membrane-bound enzyme, being associated with the endoplasmic reticulum. In 1975, W. Arion and co-workers proposed a model according to which G6Pase was thought to be a rather unspecific phosphatase, with its catalytic site oriented towards the lumen of the endoplasmic reticulum… CONTINUE READING
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Localisation of the gene for glycogen storage disease type 1c by homozygosity mapping to 11q

  • P J.
  • J. Med. Genet
  • 1998
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Mutations in the glucose-6-phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c

  • J Y.
  • J. Clin. Invest
  • 1995
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A conformational model for the human liver microsomal

  • G. de Werve
  • 1994
Highly Influential
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Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A

  • J. Y. Chou
  • J. Biol
  • 1993
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