The glucose-6-phosphatase system.

@article{Schaftingen2002TheGS,
  title={The glucose-6-phosphatase system.},
  author={Emile van Schaftingen and Isabelle Gerin},
  journal={The Biochemical journal},
  year={2002},
  volume={362 Pt 3},
  pages={513-32}
}
Glucose-6-phosphatase (G6Pase), an enzyme found mainly in the liver and the kidneys, plays the important role of providing glucose during starvation. Unlike most phosphatases acting on water-soluble compounds, it is a membrane-bound enzyme, being associated with the endoplasmic reticulum. In 1975, W. Arion and co-workers proposed a model according to which G6Pase was thought to be a rather unspecific phosphatase, with its catalytic site oriented towards the lumen of the endoplasmic reticulum… CONTINUE READING
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