The glomerular mesangial cell: an expanding role for a specialized pericyte

@article{Schlondorff1987TheGM,
  title={The glomerular mesangial cell: an expanding role for a specialized pericyte},
  author={D. Schlondorff},
  journal={The FASEB Journal},
  year={1987},
  volume={1},
  pages={272 - 281}
}
The mesangial cell occupies a central position in the renal glomerulus. It has characteristics of a modified smooth muscle cell, but is also capable of a number of other functions. Among these are generation of prostaglandins (PGs) and mediators of inflammation; production and breakdown of basement membrane and other biomatrix material; synthesis of cytokines; and uptake of macromolecules, including immune complexes. In terms of its smooth muscle activity, the mesangial cell contracts or… Expand
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