The global trace graph, a novel paradigm for searching protein sequence databases

Abstract

MOTIVATION Propagating functional annotations to sequence-similar, presumably homologous proteins lies at the heart of the bioinformatics industry. Correct propagation is crucially dependent on the accurate identification of subtle sequence motifs that are conserved in evolution. The evolutionary signal can be difficult to detect because functional sites… (More)
DOI: 10.1093/bioinformatics/btm358

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Cite this paper

@article{Heger2007TheGT, title={The global trace graph, a novel paradigm for searching protein sequence databases}, author={Andreas Heger and Swapan Mallick and Christopher Andrew Wilton and Liisa Holm}, journal={Bioinformatics}, year={2007}, volume={23 18}, pages={2361-7} }