The global status of resistance to antiretroviral drugs.

  title={The global status of resistance to antiretroviral drugs.},
  author={Stefano Vella and Lucia Palmisano},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={41 Suppl 4},
Since 1989, the emergence of resistant human immunodeficiency virus mutants has been documented for any new antiretroviral agent introduced in the clinical setting; it is a major cause of failure of antiretroviral therapy that may ultimately compromise the antiretroviral's efficacy in the general population. In most cases, resistance is due to poor adherence by the patient and/or to low potency of the therapeutic regimen. Resistance is called "primary" if detected in treatment-naive persons and… CONTINUE READING

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