The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coli.

@article{Ramseier1995TheGR,
  title={The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coli.},
  author={Tom M. Ramseier and S A Bledig and Val{\'e}rie D. Michotey and R. Feghali and Milton H. Saier},
  journal={Molecular microbiology},
  year={1995},
  volume={16 6},
  pages={1157-69}
}
The Escherichia coli fructose repressor, FruR, is known to regulate expression of several genes concerned with carbon utilization. Using a previously derived consensus sequence for FruR binding, additional potential operators were identified and tested for FruR binding in DNA band migration retardation assays. Operators in the control regions of operons concerned with carbon metabolism bound FruR, while those in operons not concerned with carbon metabolism did not. In vivo assays with… CONTINUE READING
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