The gills are an important site of iNOS expression in rainbow trout Oncorhynchus mykiss after challenge with the gram-positive pathogen Renibacterium salmoninarum.

@article{CamposPrez2000TheGA,
  title={The gills are an important site of iNOS expression in rainbow trout Oncorhynchus mykiss after challenge with the gram-positive pathogen Renibacterium salmoninarum.},
  author={Juan J Campos-P{\'e}rez and Maureen Ward and Peter S. Grabowski and Anthony E. Ellis and Christopher J Secombes},
  journal={Immunology},
  year={2000},
  volume={99 1},
  pages={153-61}
}
Following injection challenge of rainbow trout with the Gram-positive pathogen Renibacterium salmoninarum, serum nitrate levels increased indicative of NO production. The timing and amount of nitrate produced varied with the virulence of the bacterial strain used, with the highest levels seen in fish challenged with the most virulent (autoaggregating) strain. Immunization with a killed R. salmoninarum preparation in Freund's incomplete adjuvant significantly increased nitrate levels after… CONTINUE READING

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