The genotypes of IL-1 beta and MMP-3 are associated with the prognosis of HCV-related hepatocellular carcinoma.

@article{Okamoto2010TheGO,
  title={The genotypes of IL-1 beta and MMP-3 are associated with the prognosis of HCV-related hepatocellular carcinoma.},
  author={Kinya Okamoto and Chihiro Ishida and Yuichiro Ikebuchi and Mari Mandai and Kenichi Mimura and Yoshikazu Murawaki and Isao Yuasa},
  journal={Internal medicine},
  year={2010},
  volume={49 10},
  pages={887-95}
}
BACKGROUND AND AIM Cytokines and matrix metalloproteinases (MMPs) are involved in tumor growth, invasion, and remote metastasis in various cancers. Recently, functional gene polymorphisms in these cytokines and MMPs have been found, and some reports have revealed an association between these polymorphisms and the prognosis of various cancers. In this study, we examined the relationship between the gene polymorphisms of interleukin 1 beta (IL-1b), IL-1 receptor antagonist (IL-1 RN), transforming… CONTINUE READING

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