The genotoxicity of trenbolone, a synthetic steroid

  title={The genotoxicity of trenbolone, a synthetic steroid},
  author={M. Richold},
  journal={Archives of Toxicology},
  • M. Richold
  • Published 2004
  • Biology, Medicine
  • Archives of Toxicology
  • Trenbolone, a synthetic androgen is used as a growth promotant in animal husbandry. Because of its steroidal structure and properties it has been extensively evaluated in a series of in vitro and in vivo assays to assess its genotoxic and initiating properties. Both the parent molecule 17-beta-hydroxytrenbolone and its metabolite 17-alpha-hydroxytrenbolone, produced only in cattle, have been tested. 17-beta-hydroxy-trenbolone was not genotoxic in the Ames Salmonella/microsome assay… CONTINUE READING
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