The genomic landscape of the somatic linker histone subtypes H1.1 to H1.5 in human cells.

@article{Izzo2013TheGL,
  title={The genomic landscape of the somatic linker histone subtypes H1.1 to H1.5 in human cells.},
  author={Annalisa Izzo and Kinga Kamieniarz-Gdula and Fidel Ram{\'i}rez and Nighat Noureen and Jop H Kind and Thomas Manke and Bas van Steensel and Robert Schneider},
  journal={Cell reports},
  year={2013},
  volume={3 6},
  pages={2142-54}
}
Human cells contain five canonical, replication-dependent somatic histone H1 subtypes (H1.1, H1.2, H1.3, H1.4, and H1.5). Although they are key chromatin components, the genomic distribution of the H1 subtypes is still unknown, and their role in chromatin processes has thus far remained elusive. Here, we map the genomic localization of all somatic replication-dependent H1 subtypes in human lung fibroblasts using an integrative DNA adenine methyltransferase identification (DamID) analysis. We… CONTINUE READING
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