The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish

@article{Reid2016TheGL,
  title={The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish},
  author={Noah M. Reid and Dina A. Proestou and Bryan W. Clark and Wesley C. Warren and John Colbourne and Joseph R. Shaw and Sibel I. Karchner and Mark E Hahn and Diane Nacci and Marjorie F. Oleksiak and Douglas L Crawford and Andrew Whitehead},
  journal={Science},
  year={2016},
  volume={354},
  pages={1305-1308}
}
Atlantic killifish populations have rapidly adapted to normally lethal levels of pollution in four urban estuaries. Through analysis of 384 whole killifish genome sequences and comparative transcriptomics in four pairs of sensitive and tolerant populations, we identify the aryl hydrocarbon receptor–based signaling pathway as a shared target of selection. This suggests evolutionary constraint on adaptive solutions to complex toxicant mixtures at each site. However, distinct molecular variants… CONTINUE READING
43 Citations
2 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

References

Publications referenced by this paper.
Showing 1-2 of 2 references

ACKNOWLEDGMENTS Sequence data are archived at the National Center for Biotechnology Information (BioProject PRJNA323589). Phylogenetic tree data are archived at Dryad (doi: 10.5061/dryad.68n87)

  • E. M. Leffler
  • PLOS Biol. 10,
  • 2012
1 Excerpt

The AH Receptor in Biology and Toxicology

  • R. Pohjanvirta
  • 2012
1 Excerpt

Similar Papers

Loading similar papers…