The genome-wide structure of the Jewish people
@article{Behar2010TheGS, title={The genome-wide structure of the Jewish people}, author={Doron M Behar and Bayazit Yunusbayev and Mait Metspalu and Ene Metspalu and Saharon Rosset and Jüri Parik and Siiri Rootsi and Gyaneshwer Chaubey and Ildus Kutuev and Guennady Yudkovsky and Elza K. Khusnutdinova and Oleg P. Balanovsky and Ornella Semino and Lu{\'i}sa Pereira and David Comas and David Gurwitz and Batsheva Bonn{\'e}‐Tamir and Tudor Parfitt and Michael F. Hammer and Karl Skorecki and Richard Villems}, journal={Nature}, year={2010}, volume={466}, pages={238-242} }
Contemporary Jews comprise an aggregate of ethno-religious communities whose worldwide members identify with each other through various shared religious, historical and cultural traditions. [] Key Method Here we use high-density bead arrays to genotype individuals from 14 Jewish Diaspora communities and compare these patterns of genome-wide diversity with those from 69 Old World non-Jewish populations, of which 25 have not previously been reported.
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References
SHOWING 1-10 OF 33 REFERENCES
Genomic microsatellites identify shared Jewish ancestry intermediate between Middle Eastern and European populations
- BiologyBMC Genetics
- 2009
The view that the Jewish populations largely share a common Middle Eastern ancestry and that over their history they have undergone varying degrees of admixture with non-Jewish populations of European descent is supported.
Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes.
- HistoryProceedings of the National Academy of Sciences of the United States of America
- 2000
The hypothesis that the paternal gene pools of Jewish communities from Europe, North Africa, and the Middle East descended from a common Middle Eastern ancestral population is supported, and most Jewish communities have remained relatively isolated from neighboring non-Jewish communities during and after the Diaspora is suggested.
Counting the Founders: The Matrilineal Genetic Ancestry of the Jewish Diaspora
- BiologyPloS one
- 2008
The numerically major portion of the non-Ashkenazi Jews, currently estimated at 5 million people and comprised of the Moroccan, Iraqi, Iranian and Iberian Exile Jewish communities showed no evidence for a narrow founder effect, which did however characterize the smaller and more remote Belmonte, Indian and the two Caucasus communities.
The Genetic Structure and History of Africans and African Americans
- BiologyScience
- 2009
A detailed genetic analysis of most major groups of African populations is provided, suggesting that Africans represent 14 ancestral populations that correlate with self-described ethnicity and shared cultural and/or linguistic properties.
Reconstructing Indian Population History
- BiologyNature
- 2009
It is predicted that there will be an excess of recessive diseases in India, which should be possible to screen and map genetically and is higher in traditionally upper caste and Indo-European speakers.
A genetic profile of contemporary Jewish populations
- MedicineNature Reviews Genetics
- 2001
The Jews are an ancient people with a history spanning several millennia. Genetic studies over the past 50 years have shed light on Jewish origins, the relatedness of Jewish communities and the…
A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans
- BiologyGenome Biology
- 2008
It is shown that within Americans of European ancestry there is a perfect genetic corollary of Jewish ancestry which, in principle, would permit near perfect genetic inference of Ashkenazi Jewish ancestry.
Genes mirror geography within Europe
- BiologyNature
- 2008
Despite low average levels of genetic differentiation among Europeans, there is a close correspondence between genetic and geographic distances; indeed, a geographical map of Europe arises naturally as an efficient two-dimensional summary of genetic variation in Europeans.
Mapping Human Genetic Diversity in Asia
- BiologyScience
- 2009
The results suggest that there may have been a single major migration of people into Asia and a subsequent south-to-north migration across the continent, and that genetic ancestry is strongly correlated with linguistic affiliations as well as geography.
Discerning the Ancestry of European Americans in Genetic Association Studies
- BiologyPLoS genetics
- 2008
Empirical patterns of population structure in European Americans are investigated, analyzing 4,198 samples from four genome-wide association studies to show that components roughly corresponding to northwest European, southeast European, and Ashkenazi Jewish ancestry are the main sources of European American population structure.