The genome and epigenome of malignant melanoma.

  title={The genome and epigenome of malignant melanoma.},
  author={Christina Dahl and Per Guldberg},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  volume={115 10},
Malignant melanoma originates in melanocytes, the pigment-producing cells of the skin and eye, and is one of the most deadly human cancers with no effective cure for metastatic disease. Like many other cancers, melanoma has both environmental and genetic components. For more than 20 years, the melanoma genome has been subject to extensive scrutiny, which has led to the identification of several genes that contribute to melanoma genesis and progression. Three molecular pathways have been found… CONTINUE READING

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