The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.

@article{Cherian2006TheGO,
  title={The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.},
  author={Sindhu Cherian and Adam Bagg},
  journal={Hematology},
  year={2006},
  volume={11 1},
  pages={1-13}
}
Myelodysplastic syndromes (MDS) are a complex group of clonal hematopoietic disorders with an attendant diverse array of associated genetic changes. Conventional cytogenetics plays a prominent and well-established role in determining the contemporary diagnosis and prognosis of these disorders. More recently, molecular approaches have been useful in further characterizing this group of diseases, albeit in a largely experimental context, with the detection of changes at the single gene level… CONTINUE READING