The genetics of substance dependence.

  title={The genetics of substance dependence.},
  author={Jen-Chyong Wang and Manav Kapoor and Alison M. Goate},
  journal={Annual review of genomics and human genetics},
A large segment of the population suffers from addiction to alcohol, smoking, or illicit drugs. Not only do substance abuse and addiction pose a threat to health, but the consequences of addiction also impose a social and economic burden on families, communities, and nations. Genome-wide linkage and association studies have been used for addiction research with varying degrees of success. The most well-established genetic factors associated with alcohol dependence are in the genes encoding… CONTINUE READING


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