The genetics of spondyloarthropathies.

  title={The genetics of spondyloarthropathies.},
  author={Kok Yong Fong},
  journal={Annals of the Academy of Medicine, Singapore},
  volume={29 3},
  • Kok Yong Fong
  • Published 2000 in Annals of the Academy of Medicine, Singapore
INTRODUCTION Spondyloarthropathies are a heterogeneous group of rheumatic disorders that commonly present with axial skeleton or sacroiliac joints involvement. Ocular involvement like uveitis, iritis and conjunctivitis can be present in up to a third of the patients. Genetic factors play a part in the pathogenesis of spondyloarthropathies. Association with the HLA-B27 gene, especially that between ankylosing spondylitis and HLA-B27 antigenic positivity, is one of the strongest association seen… CONTINUE READING