The genetics of schizophrenia: glutamate not dopamine?

@article{Collier2003TheGO,
  title={The genetics of schizophrenia: glutamate not dopamine?},
  author={David A. Collier and Tao Li},
  journal={European journal of pharmacology},
  year={2003},
  volume={480 1-3},
  pages={177-84}
}
The major targets of current drugs used in mental health, such as neurotransmitter receptors and transporters, are based on serendipitous findings from several decades ago, and there is currently a severe drought of new drug targets. There is a pressing need for novel drugs, and much hope has been placed on the use of molecular genetics to help define them. However, despite evidence for a genetic basis to schizophrenia stretching back for over a century, and a heritability of about 80%, the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…