The genetics of psoriasis and psoriatic arthritis.

@article{Chandran2013TheGO,
  title={The genetics of psoriasis and psoriatic arthritis.},
  author={Vinod Kumar Mozhikunnam Chandran},
  journal={Clinical reviews in allergy & immunology},
  year={2013},
  volume={44 2},
  pages={
          149-56
        }
}
Genetic epidemiological studies have demonstrated a significant genetic basis to both psoriasis and psoriatic arthritis (PsA). Although candidate gene association studies had identified genes for disease susceptibility, recent genome-wide association studies have demonstrated robust associations both within and outside the major histocompatibility region on chromosome 6p. The susceptibility genes identified include HLA-C, IL13, IL4, TNFAIP3, IL23A, IL23R, IL28RA, REL, IFIH1, ERAP, TRAF3IP2… CONTINUE READING
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