The genetics of pathogen avoidance in Caenorhabditis elegans.

  title={The genetics of pathogen avoidance in Caenorhabditis elegans.},
  author={Hinrich Schulenburg and Jonathan J Ewbank},
  journal={Molecular microbiology},
  volume={66 3},
Much attention is rightly focused on how microbes cause disease, but they can also affect other aspects of host physiology, including behaviour. Indeed, pathogen avoidance behaviours are seen across animal taxa and are probably of major importance in nature. Here, we review what is known about the molecular genetics underlying pathogen avoidance in the nematode Caenorhabditis elegans. In its natural environment, the soil, this animal feeds on microbes and is continuously exposed to a diverse… CONTINUE READING

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