The genetics of inbreeding depression

@article{Charlesworth2009TheGO,
  title={The genetics of inbreeding depression},
  author={D. Charlesworth and J. Willis},
  journal={Nature Reviews Genetics},
  year={2009},
  volume={10},
  pages={783-796}
}
  • D. Charlesworth, J. Willis
  • Published 2009
  • Medicine, Biology
  • Nature Reviews Genetics
  • Inbreeding depression — the reduced survival and fertility of offspring of related individuals — occurs in wild animal and plant populations as well as in humans, indicating that genetic variation in fitness traits exists in natural populations. Inbreeding depression is important in the evolution of outcrossing mating systems and, because intercrossing inbred strains improves yield (heterosis), which is important in crop breeding, the genetic basis of these effects has been debated since the… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Genome-wide patterns of genetic variation among elite maize inbred lines
    • 393
    • PDF
    Understanding Inbreeding Depression, Purging, and Genetic Rescue.
    • 163
    • Highly Influenced
    Assisted Gene Flow to Facilitate Local Adaptation to Climate Change
    • 436
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 155 REFERENCES
    The genetic basis of inbreeding depression.
    • 668
    • PDF
    Introduction to Quantitative Genetics.
    • 13,399