The genetics of clinical outcome in multiple sclerosis

  title={The genetics of clinical outcome in multiple sclerosis},
  author={Sreeram V Ramagopalan and Gabriele C Deluca and Alexandra Degenhardt and George Cornell Ebers},
  journal={Journal of Neuroimmunology},
Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system (CNS), the clinical course of which varies considerably between patients. Genetic complexity and interactions with as yet unknown environmental factors have hindered researchers from fully elucidating the aetiology of the disease. In addition to influencing disease susceptibility, epidemiological evidence suggests that genetic factors may affect phenotypic expression of the disease. Genes that affect clinical… CONTINUE READING


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