The genetics of autistic disorders and its clinical relevance: a review of the literature

@article{Freitag2007TheGO,
  title={The genetics of autistic disorders and its clinical relevance: a review of the literature},
  author={C. Freitag},
  journal={Molecular Psychiatry},
  year={2007},
  volume={12},
  pages={2-22}
}
  • C. Freitag
  • Published 2007
  • Biology, Medicine
  • Molecular Psychiatry
Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially delineate the phenotype of AD and discuss aspects of differential diagnosis, which are particularly relevant with regard to the genetics of autism. Cytogenetic and molecular genetic studies will be presented in detail, and the possibly involved aetiopathological pathways will be described. Implications of the… Expand
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