The genetics of atherothrombotic disorders: a clinician's view

@article{Grant2003TheGO,
  title={The genetics of atherothrombotic disorders: a clinician's view},
  author={Peter J Grant},
  journal={Journal of Thrombosis and Haemostasis},
  year={2003},
  volume={1}
}
  • P. Grant
  • Published 1 July 2003
  • Biology, Medicine
  • Journal of Thrombosis and Haemostasis
Summary.  The development of coronary artery disease is dependent on the interaction of multiple biochemical pathways that lead to the development of plaque in the arterial wall and ultimately plaque instability, plaque rupture and thrombosis. The latter stages lead to vascular obstruction, tissue death and the final phenotype of myocardial infarction. Hemostasis gene association studies of atherothrombotic disorders have been unrewarding, with largely underpowered studies reporting… 
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